The mission of the Bio Fluid Mechanics Laboratory is to develop and apply state of the art engineering technology to improve the efficacy of medical practice in the areas of diagnosis, treatment and drug delivery. We are especially interested in understanding how physiology and mechanics on the cellular scale, micron and smaller, determine macro scale, organ and tissue, physiology and mechanical properties. The laboratory is well equipped to study mechanics at all scales. The lab is an ideally situated geographically to fulfill its inter-disciplinary mission, with both the University of Maryland Medical School and The Johns Hopkins University School of Medicine less than ten miles from campus. Current research efforts are aimed at the interplay between mechanics and physiology at the cellular and macroscale and include Developing models of cellular deformation and interaction with other cells in order to understand and control cellular adhesion. For instance, we may want to enhance luekocyte adhesion in order to fight off infections, and we may want to disrupt bacterial adhesion in order to prevent infections. Use Computational Fluid Mechanics to characterize flow in stirred tank bioreactors from the cell prespective (Lagrangian reference frame) in order to improve the productivity of fed batch fermentations