BIOLOGY 302
MOLECULAR AND GENERAL GENETICS
FALL, 2006
Professor: Dr. Richard C. Gethmann, BS 117, (410) 455-2470 gethmann@umbc.edu
Prerequisite: "C" or better in Biol 100 and Chem 101 (or Chem 123); sophomore
standing.
Corequisite: enrollment in Chem 102 (or Chem 124)
Text: "GENETICS: Analysis of Genes and Genomes", 6th Ed., by Daniel L. Hartl and Elizabeth W. Jones
The class Web site is http://www.umbc.edu/bioclass/biol302
Lecture meeting time: Tuesday and Thursday, 9:20 - 11:15 AM, LH2
Biology Tutorial Center: The Biology Tutorial Center is located in room 011 in the basement of the Biological Sciences building. Hours and time are posted.
Grading Policy and exam schedule:
The final grade will be based upon your performance in three of the four scheduled midterm exams, plus the comprehensive final exam, plus any unannounced quizzes. Each midterm exam is worth 100 points, the final exam is worth 150 points.
Exam schedule:
Exam 1 Tuesday Sept. 26
Exam 2 Tuesday Oct. 17
Exam 3 Thursday Nov. 9
Exam 4 Tuesday Dec. 5
Final Wednesday Dec. 20
Times, room assignments, and any other special instructions for the exams will be given in class.
Since your lowest midterm exam score will be dropped, make up exams will not be given except for extreme situations (such as an extended illness). To be eligible for a possible make up exam, you must notify either me or the Biology Department Office (410-455-2261) prior to the exam. The form and the time of the make-up exam will be at the discretion of the instructor.
POLICY ON ACADEMIC MISCONDUCT
Any confirmed case of cheating on an exam will be dealt with through UMBCs Academic Conduct Committee as described in the Policy for Academic Misconduct in Undergraduate courses. Penalties include, but are not limited to, a grade of F in the class.
LECTURE TOPICS, READINGS & PROBLEM SETS
| Topics | Hartl & Jones | Problems |
| Introduction | 2 - 16; 25 - 27 | |
| Nucleic acid structure | 44 - 51; 222 - 229 | |
| Chromosome structure | 262 - 272; 277 - 286 | |
| Cell Division | 134 - 149 | 4.2, 4.3, 4.5, 4.6 |
| Monohybrid crosses: | ||
| Mendel's experiments | 88 - 100 | 3.1, 3.3, 3.4, 3.8, 3.13 |
| Multiple alleles, codominance | 112 - 116 | |
| Sex Linkage | 150 - 156 | 4.10, 4.13, 4.14, 4.20, 4.21 |
| Sex determination and Dosage compensation | 157 - 159; 301 -305 | |
| Probability and Chi-square | 109 - 112; 162 -165 | 4.28, 4.29, 4.30 |
| Dihybrid crosses: | ||
| unlinked genes | 100 -103; 116 - 124 | 3.12, 3.19, 3.21, 3.22 |
| linked genes and mapping | 178 - 188; 194 -197 | 5.1, 5.18, 5.19, 5.21 |
| Gene Action (overview) | 400 - 402 | |
| Replication | 230 - 241 | |
| Transcription | 403 - 417 | |
| Translation | 417 - 433 | |
| Mutation & repair | 592 - 604 | 14.1, 14.5, 14.10, 14.12 |
| Transposable Elements | 605 - 612 | |
| Bacterial genetics | 346 - 369 | 9.10, 9.13, 9.14, 9.16, 9.20 |
| Gene Regulation | 445 - 460; 482 - 483 | 11.1, 11.4, 11.14, 11.17, 11.18 |
| Genetics and Cancer | 644 - 646; 650 - 676 | |
| Recombinant DNA Technology | 53 - 74; 76 -78; 241 - 243 | 2.5, 2.6, 2.7, 2.18, 2.20, 2.21 |
| Applications of Recombinant DNA Technology | 502 - 514; 530 - 535 | 12.17, 12.26, 12.27 |
| Population genetics | 725 - 731; 735 - 751 | 17.1, 17.3, 17.5, 17.7, 17.8, 17.13, 17.14, 17.17 |
| Aneuploidy & Euploidy | 309 - 315; 329 - 330 | 8.1, 8.2, 8.4, 8.5, 8.9 |
