BIOLOGY 302
MOLECULAR AND GENERAL GENETICS
FALL, 2006


Professor: Dr. Richard C. Gethmann, BS 117, (410) 455-2470 gethmann@umbc.edu

Prerequisite: "C" or better in Biol 100 and Chem 101 (or Chem 123); sophomore
standing.

Corequisite: enrollment in Chem 102 (or Chem 124)

Text: "GENETICS: Analysis of Genes and Genomes", 6th Ed., by Daniel L. Hartl and Elizabeth W. Jones

The class Web site is http://www.umbc.edu/bioclass/biol302

Lecture meeting time: Tuesday and Thursday, 9:20 - 11:15 AM, LH2

Biology Tutorial Center: The Biology Tutorial Center is located in room 011 in the basement of the Biological Sciences building. Hours and time are posted.


Grading Policy and exam schedule:

The final grade will be based upon your performance in three of the four scheduled midterm exams, plus the comprehensive final exam, plus any unannounced quizzes. Each midterm exam is worth 100 points, the final exam is worth 150 points.

Exam schedule:

Exam 1 Tuesday Sept. 26
Exam 2 Tuesday Oct. 17
Exam 3 Thursday Nov. 9
Exam 4 Tuesday Dec. 5
Final Wednesday Dec. 20

Times, room assignments, and any other special instructions for the exams will be given in class.

Since your lowest midterm exam score will be dropped, make up exams will not be given except for extreme situations (such as an extended illness). To be eligible for a possible make up exam, you must notify either me or the Biology Department Office (410-455-2261) prior to the exam. The form and the time of the make-up exam will be at the discretion of the instructor.


POLICY ON ACADEMIC MISCONDUCT

Any confirmed case of cheating on an exam will be dealt with through UMBC’s Academic Conduct Committee as described in the Policy for Academic Misconduct in Undergraduate courses. Penalties include, but are not limited to, a grade of “F” in the class.

LECTURE TOPICS, READINGS & PROBLEM SETS

Topics Hartl & Jones Problems
     
Introduction 2 - 16; 25 - 27  
     
Nucleic acid structure 44 - 51; 222 - 229  
     
Chromosome structure 262 - 272; 277 - 286  
     
Cell Division 134 - 149 4.2, 4.3, 4.5, 4.6
     
Monohybrid crosses:    
Mendel's experiments 88 - 100 3.1, 3.3, 3.4, 3.8, 3.13
Multiple alleles, codominance 112 - 116  
Sex Linkage 150 - 156 4.10, 4.13, 4.14, 4.20, 4.21
     
Sex determination and Dosage compensation 157 - 159; 301 -305  
     
Probability and Chi-square 109 - 112; 162 -165 4.28, 4.29, 4.30
     
Dihybrid crosses:    
unlinked genes 100 -103; 116 - 124 3.12, 3.19, 3.21, 3.22
linked genes and mapping 178 - 188; 194 -197 5.1, 5.18, 5.19, 5.21
     
Gene Action (overview) 400 - 402  
Replication 230 - 241  
Transcription 403 - 417  
Translation 417 - 433  
Mutation & repair 592 - 604 14.1, 14.5, 14.10, 14.12
     
Transposable Elements 605 - 612  
     
Bacterial genetics 346 - 369 9.10, 9.13, 9.14, 9.16, 9.20
     
Gene Regulation 445 - 460; 482 - 483 11.1, 11.4, 11.14, 11.17, 11.18
     
Genetics and Cancer 644 - 646; 650 - 676  
     
Recombinant DNA Technology 53 - 74; 76 -78; 241 - 243 2.5, 2.6, 2.7, 2.18, 2.20, 2.21
Applications of Recombinant DNA Technology 502 - 514; 530 - 535 12.17, 12.26, 12.27
     
Population genetics 725 - 731; 735 - 751 17.1, 17.3, 17.5, 17.7, 17.8, 17.13, 17.14, 17.17
     
Aneuploidy & Euploidy 309 - 315; 329 - 330 8.1, 8.2, 8.4, 8.5, 8.9