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UMBC Biology
Group Wiki Assignment
The second written assignment is to develop as a group a set of pages in the class Wiki site that explore issues having to do with transcription and transcriptional control in eukaryotes.
Topics:
  1. Promoter recognition:
    What is the structural basis of promoter recognition?
  2. Basal factor kinases:
    How does phosphorylation of the basal transcription machinery regulate initiation and elongation?
  3. Histone code:
    In what ways does histone modification regulate transcription?
  4. Co-transcriptional processing:
    What mechanisms coordinate co-transcriptional processing of mRNAs?
  5. RNA transport:
    How are mRNAs targeted for transport out of the nucleus and into the cytoplasm?
  6. RNA degradation:
    What is the mechanism of degradation of normal mRNAs and aberrant mRNAs?
  7. RNA editing:
    How are RNAs modified post transcriptionally to change their primary sequence?
Each group Wiki site should explore the assigned topic as fully as possible. The site should reference a body of the primary research literature and discuss how our current understanding of each process has been established.
Links to the group wiki sites