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Proteomics:
Brian Bradley
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Proteomics,
particularly the expression of specific sets of proteins in
response to environmental conditions, is the research theme
in Dr. Brian Bradley’s lab. His research group uses the
proteins to detect environmental hazards. “We focus on
diagnosis or prognosis of stress by examining multiple |
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in Protein Expression Signatures,” says Bradley, who has
been a faculty member in the Biological Sciences Department
since 1970. “In principle, we can detect a component stressor—chemical
or biological—in a complex environment.” |
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The many applications
of Proteomics have generated significant interest in Bradley’s
research, which is supported by funding from the Environmental Protection
Agency, Oakridge National Labs, the Department of Defense (U.S.
Army), and a National Oceanic and Atmospheric Administration (NOAA)
Sea Grant. Two patents protect the technology and a third one is
pending. “We use multiple indicators as opposed to single indicators
used now, which makes it more powerful,” explains Bradley.
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| Recent applications by
the lab include determining what makes mussels and oysters ill and
using soil organisms to identify chemicals that may harm the health
of deployed troops. |
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