C. elegans serves as an excellent model system for studying cell signaling, cell fate Determinization, and morphogenesis. Vulval development in C. elegans is regulated by the conserved Ras, Notch, and Wnt cell signaling pathways. Protruding vulva mutants identified a series of genes involved in vulval development. One of the genes identified was bar-1, which showed homology with Beta Catenin/Armadillo, a member of the Wnt signaling family of proteins. The bar-1 gene encodes a transcription factor that regulates the Hox gene lin-39. LIN-39, another transcription factor, regulates egl-18, which encodes a GATA transcription factor. My project is to identify other genes involved in the Wnt-like pathway for the developing vulva.