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Undergraduate Catalog 2011

Chemistry and Biochemistry

Faculty

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Professors

C. Allen Bush
James C. Fishbein
Chris Geddes
Upal Ghosh
Richard L. Karpel
Joel F. Liebman
Gregory Payne
Brian Reed
Michael F. Summers
Claire Welty

Associate Professors

Bradley R. Arnold
Brian M. Cullum
Lisa A. Kelly
Katherine L. Seley-Radtke
Paul J. Smith

Senior Lecturer

H. Mark Perks

Assistant Professors

Marie-Christine Daniel-Onuta
Elsa D. Garcin
Marcin Ptaszek
Ian F. Thorpe

Instructors

Tara Carpenter
Tiffany Gierasch
Diane Hamilton
Stephen Mang
Alllison Tracy

Adjunct Faculty

Aristotle G. Kalivretenos
Wuyuan Lu
Lei-Xi Wang

Affiliate Faculty

Linda Hodges
Ana Prados
Katherine Squibb

Professor Emeritus

Fred Gornick
Arthur S. Hyman
Ralph Pollack
Dale L. Whalen

Associate Professor Emeritus

James S. Vincent

Professor and Chair

William R. LaCourse

Lecturer

Joshua Enszer

Courses in this program are listed under CHEM.

The undergraduate programs in chemistry and biochemistry offer students the opportunity to study in a program tailored to meet their career objectives in a department that is large enough to provide excellent training and research facilities and small enough to encourage a close working relationship with professors. The experienced, dynamic faculty of the department present outstanding credentials, with advanced degrees and post-doctoral training from some of the most prestigious schools in the world. They are devoted to both teaching and research. Their scientific and scholarly achievements attract close to $4 million in funding per year, resulting in many opportunities for students to participate in undergraduate research in faculty labs and to gain exposure to cutting-edge science in their classrooms.

The department offers three major programs: the B.S. in Chemistry, a rigorous program certified by the American Chemical Society; a B.A. in Chemistry, which provides the option of an increased number of electives so the student may combine a solid background in chemistry with other areas of interest, such as law, education, business management or environmental sciences.; and a B.S. in Biochemistry and Molecular Biology (jointly with the Department of Biological Sciences). A combined chemistry B.S./M.S. and or a minor in chemistry are also available to qualified students. In conjunction with the education department, a program leading to a B.A in Chemistry Education with an emphasis in either Biochemistry or Physical Chemistry may be pursued.

The programs of the chemistry and biochemistry department periodically are reviewed by the American Chemical Society (ACS), the professional organization that sets the standards for chemical education, and UMBC chemistry students consistently place at, or above, the norm in their standardized examinations. The B.S. degree in chemistry is accredited by the ACS. In a recent report, the ACS ranked UMBC 23rd in the nation as far as the number of chemistry/biochemistry graduates it produced.

Career and Academic Paths

More than 60 percent of the department’s graduates pursue further education (graduate programs in chemistry and biochemistry) or professional training (medical, dental, pharmacy, nutrition, veterinary medicine and environmental science) at such distinguished schools as Harvard; MIT; Oxford; The Johns Hopkins University; Stanford; University of Virginia and University of Maryland, Baltimore. Many students choose to continue post-baccalaureate studies at UMBC, enrolling in the M.S. or Ph.D. programs in chemistry, the M.S. or Ph.D. programs in biochemistry (joint with UMB) or molecular and cell biology, or the M.S. program in applied molecular biology (joint with the Department of Biological Sciences).
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Academic Advising

The department assigns students to faculty advisors based upon the student’s declared major of either chemistry or biochemistry. After filing a Declaration of Major form, students should contact the department office.
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Major Programs

Note: Chemistry, math and physics courses that serve as prerequisites for other chemistry courses must be satisfied with no less than a grade of ”C”; The cumulative grade point average of courses
required for the undergraduate chemistry major must be at least 2.0. *(MATH 251, required by the B.S. program, must be completed with no less than a grade of *“*C.”)

Bachelor of Science (B.S.) Chemistry The Bachelor of Science in Chemistry, which provides graduates with an American Chemical Society-certified degree, consists of at least 72 credits distributed as follows:

A. Chemistry (49 credits)

  • CHEM 101 Principles of Chemistry I
  • CHEM 102 Principles of Chemistry II
  • CHEM 102L Introductory Chemistry Lab
  • CHEM 351 Organic Chemistry I
  • CHEM 352 Organic Chemistry II
  • CHEM 351L Organic Laboratory I
  • CHEM 352L Organic Laboratory II
  • CHEM 300 Analytical Chemistry
  • CHEM 301 Physical Chemistry
  • CHEM 302 Physical Chemistry II
  • CHEM 311L Advanced Laboratory I
  • CHEM 312L Advanced Laboratory II
  • CHEM 405 Inorganic Chemistry
  • CHEM 405L Advanced Inorganic Chemistry Laboratory
  • CHEM 420 Scientific Computing
  • CHEM 461 Advanced Instrumental Analysis

Biochemistry Requirement:

  • CHEM 437 Biochemistry
    OR
  • CHEM 455 Biomedicinal Chemistry
    OR
  • CHEM 470 Toxicology

B. Mathematics (12 credits)

  • MATH 151 Calculus and Analytic Geometry I
  • MATH 152 Calculus and Analytic Geometry II
  • MATH 251 Multivariable Calculus

C. Physics (8 credits)

  • PHYS 121 Introductory Physics I
  • PHYS 122 Introductory Physics II

D. Approved Electives (3 credits)

  • CHEM 401 Chemical and Statistical Thermodynamics
  • CHEM 406 Bioinorganic Chemistry
  • CHEM 410 Quantum Chemistry
  • CHEM 415 Statistical Mechanics and Theories of Rate Processes
  • CHEM 431 Chemistry of Proteins
  • CHEM 432 Advanced Biochemistry
  • CHEM 433 Biochemistry of Nucleic Acids
  • CHEM 435 Biochemistry of Complex Carbohydrates
  • CHEM 437 Comprehensive Biochemistry I
  • CHEM 437L Biochemistry Laboratory
  • CHEM 438 Comprehensive Biochemistry II
  • CHEM 441 Physical Chemistry of Macromolecules
  • CHEM 442 Physical Biochemistry
  • CHEM 443 Molecular Spectroscopy and Biomacromolecules
  • CHEM 444 Molecular Modeling
  • CHEM 450 Chemistry of Heterocyclic Compounds
  • CHEM 451 Mechanisms of Organic Reactions
  • CHEM 452 Physical Organic Chemistry
  • CHEM 453 Organic Chemistry of Nucleic Acids
  • CHEM 455 Introduction to Biomedicinal Chemistry
  • CHEM 457 Total Synthesis of Natural Products
  • CHEM 465 Mass Spec at the Chemistry-Biochemistry Interface
  • CHEM 470 Toxicological Chemistry
  • CHEM 472 Enzyme Reaction Mechanisms
  • CHEM 499* Undergraduate Research

Qualified undergraduates also may enroll in graduate courses offered by the department. Specific graduate-level, current or special topics courses may be approved as chemistry electives when their topic is appropriate.

Bachelor of Arts (B.A.) Chemistry The Bachelor of Arts in Chemistry consists of at least 61 credits distributed as follows:


A. Chemistry (36 credits)

  • CHEM 101 Principles of Chemistry I
  • CHEM 102 Principles of Chemistry II
  • CHEM 102L Introductory Chemistry Lab
  • CHEM 351 Organic Chemistry I
  • CHEM 352 Organic Chemistry II
  • CHEM 351L Organic Laboratory I
  • CHEM 352L Organic Laboratory II
  • CHEM 300 Analytical Chemistry
  • CHEM 301 Physical Chemistry I
  • CHEM 302 Physical Chemistry II
  • CHEM 311L Advanced Laboratory I
  • CHEM 405 Inorganic Chemistry

B. Mathematics (8 credits)

  • MATH 151 Calculus and Analytic Geometry I
  • MATH 152 Calculus and Analytic Geometry II

C. Physics (8 credits)

  • PHYS 121 Introductory Physics I
  • PHYS 122 Introductory Physics II

D. Approved Electives (9 credits)

Bachelor of Science (B.S.) Biochemistry and Molecular Biology

Course requirements for the biochemistry and molecular biology B.S. are listed in the catalog section describing the Biochemistry and Molecular Biology Program.

General Information

University requirements specify that students must complete at least 120 academic credits with a cumulative grade point average of 2.0 or better. At least 45 of those credits must be in courses designated at UMBC by a 300- or 400-level course number.

Students planning to major in chemistry should begin their first course in chemistry during the first semester of the freshman year to complete the required core of credits. Such students are urged to
fulfill the requirements in mathematics and physics during their freshman and sophomore years. To do so within this period, it is strongly recommended that a course in calculus be taken promptly in the
freshman year and that the appropriate physics courses be taken no later than the sophomore year. Suggested partial programs for each degree are listed below. Both sample programs are designed for students prepared to begin MATH 151 during the first semester. If a student requires the pre-calculus course, MATH 150, it should be taken first semester and the calculus sequence begun immediately thereafter. In each case, the sequence of chemistry courses is the same.

Sample Program Bachelor of Science in Chemistry Note: Chemistry,math and physics courses that serve as prerequisites for other chemistry courses must be satisfied with no less than a grade of “C.”
The cumulative grade point average of courses required for the undergraduate chemistry major must be at least 2.0.

* MATH 251, required by the B.S. program, must be completed with no
less than a grade of “C.”

**CHEM 437, 455 or 470 may be used for the biochemistry requirement.

Freshman Fall: CHEM 101  Spring:MATH 151 PHYS 121 CHEM 102 CHEM
102L MATH 152
Sophomore Fall: CHEM 300 CHEM 351 CHEM 351L MATH 251 Spring:  CHEM 352
CHEM 352L PHYS 122
Junior Fall: CHEM 301 CHEM 311L  Spring: CHEM 302 CHEM 312L CHEM 405
Senior Fall: CHEM 420 CHEM 405L Biochem req. Spring:  CHEM 461 Approved elective

Sample Program Bachelor of Arts in Chemistry

Freshman Fall: Spring: CHEM 101 CHEM 102 MATH 151 CHEM 102L MATH 152
Sophomore Fall: CHEM 351 CHEM 351L CHEM 300 PHYS 121 Spring:  CHEM 352
CHEM 352L PHYS 122
Junior Fall: CHEM 301 CHEM 311L Spring:  CHEM 302, CHEM 405
Senior Fall: Approved Elective Spring: Approved elective.

Bachelor of Arts (B.A.), Chemistry Education, Biochemistry

The goal of UMBC's B.A. in Chemistry Education is to provide a curriculum that, in four years, gives students a solid foundation in chemistry and also the coursework necessary for certification to teach chemistry at the secondary level. It is considered crucial that graduates be fully-trained chemists, capable of working in a range of technical positions outside of secondary education. The curriculum also seeks to expand the scientific background/perspective of graduates by requiring courses in other scientific disciplines as well as a science history course.

The Bachelor of Arts in Chemistry Education, Biochemistry consists of at least 107 credits distributed as follows:

*These courses must be completed with a grade of C or better. An overall C average must be maintained in required major courses.

A. Chemistry (35 credits)

  • CHEM 101 Principles of Chemistry I*
  • CHEM 102 Principles of Chemistry II*
  • CHEM 102L Introductory Chemistry Lab*
  • CHEM 300 Analytical Chemistry
  • CHEM 303 Physical Chemistry for Biochemists*
  • CHEM 351 Organic Chemistry I*
  • CHEM 351L Organic Laboratory I*
  • CHEM 352 Organic Chemistry II*
  • CHEM 405 Inorganic Chemistry
  • CHEM 437 Biochemistry
  • CHEM 437L Biochemistry Lab

B. Mathematics (8 credits)

  • MATH 151 Calculus and Analytic Geometry I*
  • MATH 152 Calculus and Analytic Geometry II*

C. Physics (8 credits)

  • PHYS 121 Introductory Physics I*
  • PHYS 122 Introductory Physics II*

D. Education (33 credits)

  • EDUC 310 Inquiry into Education
  • EDUC 311 Psychological Foundations of Education
  • EDUC 388 Inclusion and Instruction
  • EDUC 410 Reading in the Content Area – Part I
  • EDUC 411 Reading in the Content Area – Part II
  • EDUC 412 Analysis of Teaching and Learning
  • EDUC 427 Teaching Science in the Secondary School
  • EDUC 456 Internship in Secondary Education
  • EDUC 457 Internship Seminar in Secondary Educuation

E. Other (22 credits)

  • Biol 100 Concepts of Biology
  • ENGL 100 Composition (or qualifying score on placement, 100A or 110)
  • PSYC 100 Introduction to Psychology
  • HIST 110 Western Civ to 1700 or HIST 111 – Western Civ 1700 to present
  • HIST 445 History of Science to 1700 or HIST 446 – History of Science since 1700
  • GES Elective

F. Approved Electives

  • Arts and Humanities (3 courses required) 300 or 400 Level
  • Language and Culture (3 courses required)300 or 400 Level
  • Science Course (CHEM, BIOL, PHYS: 3-4 credits required)
  • Physical Education (2 courses required)

Sample Program

Freshman

Fall

  • MATH 151
  • MATH 101
  • Arts & Humanities Elective I
  • Language/Culture Elective I
  • ENGL 101

Spring

  • MATH 152
  • CHEM 102
  • CHEM 102L
  • Language/Culture Elective II
  • PSYC 101

Sophmore

Fall

  • CHEM 351
  • CHEM 351L
  • PHYS 121
  • Language/Culture Elective III
  • HIST 110 or HIST 111

Spring

  • CHEM 352
  • PHYS 122
  • BIOL 100
  • Arts & Humanities Elective II
  • EDUC 310

Junior

Fall

  • CHEM 300*
  • CHEM 437*
  • GES Elective or HIST 445
  • EDUC 311
  • EDUC 412

Spring

  • CHEM 303*
  • CHEM 437L*
  • GES Elective or HIST 446
  • Arts & Humanities Elective III
  • EDUC 410

Senior

Fall

  • CHEM 405
  • Science Elective**
  • EDUC 427
  • EDUC 438
  • EDUC 411

Spring

  • EDUC 456
  • EDUC 457

*denotes courses that differ between Physical Chemistry and
Biochemistry tracks

**any 300 or 400 level CHEM, BIOL, or PHYS course

Two Physical Education Courses are also required for all Majors

Bachelor of Arts (B.A.), Chemistry Education, Physical Chemistry

The goal of UMBC's B.A. in Chemistry Education is to provide a curriculum that, in four years, gives students a solid foundation in chemistry and also the coursework necessary for certification to teach chemistry at the secondary level. It is considered crucial that graduates be fully-trained chemists, capable of working in a range of technical positions outside of secondary education. The curriculum also seeks to expand the scientific background/perspective of graduates by requiring courses in other scientific disciplines as well as a science history course.

The Bachelor of Arts in Chemistry Education, Physical Chemistryconsists of at least 106 credits distributed as follows:

*These courses must be completed with a grade of C or better. An overall C average must be maintained in required major courses.

A. Chemistry (35 credits)

  • CHEM 101 Principles of Chemistry I*
  • CHEM 102 Principles of Chemistry II*
  • CHEM 102L Introductory Chemistry Lab*
  • CHEM 300 Analytical Chemistry
  • CHEM 301 Physical Chemistry*
  • CHEM 302 Physical Chemistry II
  • CHEM 311L Advanced Laboratory I
  • CHEM 351 Organic Chemistry I*
  • CHEM 351L Organic Laboratory I*
  • CHEM 352 Organic Chemistry II*
  • CHEM 405 Inorganic Chemistry

B. Mathematics (8 credits)

  • MATH 151 Calculus and Analytic Geometry I*
  • MATH 152 Calculus and Analytic Geometry II*

C. Physics (8 credits)

  • PHYS 121 Introductory Physics I*
  • PHYS 122 Introductory Physics II*

D. Education (33 credits)

  • EDUC 310 Inquiry into Education
  • EDUC 311 Psychological Foundations of Education
  • EDUC 388 Inclusion and Instruction
  • EDUC 410 Reading in the Content Area – Part I
  • EDUC 411 Reading in the Content Area – Part II
  • EDUC 412 Analysis of Teaching and Learning
  • EDUC 427 Teaching Science in the Secondary School
  • EDUC 456 Internship in Secondary Education
  • EDUC 457 Internship Seminar in Secondary Educuation

E. Other (22 credits)

  • Biol 100 + BIOL 100L Concepts of Biology
  • ENGL 100 Composition (or qualifying score on placement, 100A or 110)
  • PSYC 100 Introduction to Psychology
  • HIST 110 Western Civ to 1700 or HIST 111 – Western Civ 1700 to present
  • HIST 445 History of Science to 1700 or HIST 446 – History of Science since 1700
  • GES Elective

F. Approved Electives

  • Arts and Humanities (3 courses required) 300 or 400 Level
  • Language and Culture (3 courses required)300 or 400 Level

Sample Program

Freshman

Fall

  • MATH 151
  • MATH 101
  • Arts & Humanities Elective I
  • Language/Culture Elective I
  • ENGL 101

Spring

  • MATH 152
  • CHEM 102
  • CHEM 102L
  • Language/Culture Elective II
  • PSYC 101

Sophmore

Fall

  • CHEM 351
  • CHEM 351L
  • PHYS 121
  • Language/Culture Elective III
  • HIST 110 or HIST 111

Spring

  • CHEM 352
  • CHEM 300
  • PHYS 122
  • Arts & Humanities Elective I
  • EDUC 310

Junior

Fall

  • CHEM 301*
  • CHEM 311L*
  • GES Elective or HIST 445
  • EDUC 311
  • EDUC 412

Spring

  • CHEM 302*
  • BIOL 100 & BIOL 100L
  • GES Elective or HIST 446
  • Arts & Humanities Elective
  • EDUC 410

Senior

Fall

  • CHEM 405
  • Science Elective**
  • EDUC 427
  • EDUC 438
  • EDUC 411

Spring

  • EDUC 456
  • EDUC 457

*denotes courses that differ between Physical Chemistry and Biochemistry tracks

**any 300 or 400 level CHEM, BIOL, or PHYS course

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Minor Program & Non-Majors

Any student, except those majoring in biochemistry, may complete a formal minor in chemistry. The chemistry minor thoroughly covers the basic chemical principles and offers opportunities for advanced study that can be tailored to the student’s particular interests. The minor consists of a minimum of 26 credits and will include advanced course work in biochemistry, organic, inorganic, physical or analytical chemistry. Students interested in completing a minor in chemistry may get more complete information from the department office (Chemistry Building, room 100).

Outside of the major and minor programs, the chemistry curriculum is designed to meet the needs of students with diverse goals. Biological sciences majors, as well as students preparing for entrance into schools of dentistry, medicine, pharmacy, veterinary medicine or programs in medical technology should complete CHEM 101, 102, 102L, 351, 351L, 352 and 352L. Students preparing for programs in dental hygiene, nursing and physical therapy should complete CHEM 123, 124 and 124L.

Chemistry Minor Program

The chemistry minor consists of a minimum of nine courses/ 26 credits. Core Courses (Required)

  • CHEM 101 Principles of Chemistry I [4]
  • CHEM 102 Principles of Chemistry II [3]
  • CHEM 102L Introductory Chemistry Laboratory I [2]
  • CHEM 351 Organic Chemistry I [3]
  • CHEM 351L Organic Chemistry Laboratory I [2]
  • CHEM 352 Organic Chemistry II [3]
  • CHEM 352L Organic Chemistry Laboratory II [2]
  • CHEM 300 Analytical Chemistry [4]
  • Required Electives CHEM 301 Physical Chemistry [4] OR CHEM 303 [3] OR CHEM 4XX [3]

Any upper-level chemistry course with the approval of the department chair or with the student’s chemistry advisor.

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Honors Program

The department does not offer an honors track, however specific honors sections of chemistry courses are offered. CHEM 101H and 102H, Introductory Chemistry I and II, are offered in the fall and spring, respectively. In addition, upper-level honors courses are offered in selected topics. Departmental honors are awarded to graduates in chemistry or biochemistry who achieve scholastic excellence, which is defined as a GPA of 3.5 or better in all chemistry and biochemistry courses, combined with an overall GPA of at least 3.0. At least 18 credit hours in the major must be completed at UMBC.
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Combined B.S./M.S. Graduate Program

This program is open to advanced undergraduates of superior ability. To be considered for the combined B.S./M.S. program in chemistry, undergraduate students should declare their intentions to apply to the program no later than the first semester of their senior year. This declaration should be in writing to the graduate program director in chemistry. In addition, the student must apply for admission to the Graduate School one semester prior to completion of requirements for the bachelor’s program. A maximum of nine credits of graduate-level courses may be taken at the undergraduate level. The B.S. degree may be awarded after the department requirements are met and 120 or more credits are earned. The student must be enrolled in the Graduate School while the remaining 21 or more required graduate-level credits are earned. The M.S. may be granted upon completion of the program requirements for the master’s degree and after a minimum of 141 credits total are earned for the combined degree. To remain in the program, a student is required to maintain an overall grade point average of 3.0 or better and to receive no grade lower than a “B” in any course required for the major. A requirement to participate in advanced research is an important aspect of the program. This may be done by either thesis or non-thesis options, as described below. Requirements Undergraduate:The requirements for the B.S. phase of the combined B.S./M.S. degree are identical to the normal chemistry B.S. with two exceptions:

A) The graduate-level CHEM 661: Advanced Instrumental Analysis is taken instead of the undergraduate-level equivalent CHEM 461,

AND

B) A minimum of two of the six credits of approved electives in the undergraduate phase should be at the 600-level for transfer in satisfaction of the M.S. degree requirements.

Graduate: A candidate for the combined B.S./M.S. degree must complete a total of 30 credit hours of graduate-level course work, 18 of which must be at the 600 level or above. A total of nine chemistry graduate-level credits, taken during the undergraduate period to fulfill the B.S. core requirements, will be accepted as partially meeting the master’s core requirements. The remaining 21 credit hours include the rest of the master’s-level core courses, the elective courses in chemistry and the research component. The student must be enrolled in the graduate school while the final 21 or more credits are earned.

Students may elect either a thesis option, completing six credit hours of research or a non-thesis option in which additional course work is combined with an advanced laboratory project for research experience.

Sample Program

A. Nine credits at the B.S.

  • Graduate-level courses accepted:
  • CHEM 405 Inorganic Chemistry [3]
  • CHEM 661 Advance Instrumental Analysis [4]
  • CHEM 6XX Graduate-level elective ;[2 or 3]

B. 21 credits at the M.S. level:

  • Two of the following three courses [6-7]:
  • CHEM 437 Comprehensive Biochemistry I [4]
  • OR CHEM 401 Thermodynamics [3]
  • OR CHEM 451 Mechanisms of Organic Reactions [3]

C. Thesis Option:

  • CHEM 799 M.S. Thesis Research [6]
  • CHEM 4XX-6XX Electives [8-9]

D. Non-Thesis Option:

  • CHEM 600 Advanced Laboratory Project [1]
  • CHEM 4XX-6XX Electives [13-14]

In addition, a final examination will be arranged in accord with procedures of the graduate school. This examination will follow completion of formal coursework and the submission of either the master’s thesis or, in the case of the non-thesis option, a scholarly paper indicating the student’s familiarity with an area of modern chemical research.

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Special Opportunities

Undergraduate research performed under faculty mentors within the department is encouraged. Participating students may receive credit toward graduation for this research through two upper-level courses. CHEM 399: Tutorial Projects in Chemistry, provides an introduction to research and may be taken for one to three credits. CHEM 499: Undergraduate Research is an approved elective for the American Chemical Society-certified B.S. in Chemistry and requires preparation of a formal paper based on the student’s original research. A maximum of six credits of CHEM 499 or a maximum of eight credits from the combination of BIOL 398, 399, 499, CHEM 399 and 499 may be taken. The department also offers industrial internships with various partners for additional hands-on experience. The Vitullo Award is presented each year to a junior or senior student working in a faculty member’s laboratory excelling in undergraduate research in the department.

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Honors and Awards

A number of awards are conveyed to deserving students each spring. Among them are the Vitullo Award , Mittino award, Creighton award and Satterfield award.
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Chemistry Tutorial Center

The Chemistry Tutorial Center is staffed by a full-time chemistry instructor and 25 advanced undergraduates who provide free tutoring for students in freshman and sophomore chemistry courses. Small group tutoring and computer-assisted, special topics lessons are available.
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Student Organizations

American Chemical Society Student Affiliate (ACSSA)Chapter Chemistry/Biochemistry Council of Majors An American Chemical Society (ACS) student affiliate chapter supports an active lecture and tour program to acquaint UMBC students with various career options. The ACSSA outreach program into local elementary schools involves mentoring young students, as well as providing a program of science demonstrations to assist instructors in teaching chemical principles. The ACS affiliate chapter also sponsors the presentation of several undergraduate research projects at the student session of the national ACS meeting each year.
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