Ph.D. UMBC 2012; B.S. Villanova University 2006
Synthetic Organic Chemistry and Nanomaterials Design:
Preparation and characterization of multifunctional nanovectors primarily based on gold nanoparticles and dendrons for the optimization of drug efficiency, especially in cancer and gene therapy. By using a central anchoring gold nanoparticle and attaching dendron units with distinct functionalities, it will be possible to generate a potent drug delivery vehicle for different tumor therapies. These functionalities consist of chemotherapeutic drugs, targeting ligands and imaging enhancers. Research focus includes synthesis and characterization of the gemcitabine functionalized dendron and the transferrin protein functionalized dendron for the specific application of advanced pancreatic cancer.