Event Summary:
A one-day workshop organized by the Center for Interdisciplinary Research and
Consulting at the University of Maryland, Baltimore County (UMBC), and the
Center for Innovative Study Design (CISD) at Stanford University in the field of Clinical Trials and Regulatory Science.
Registration is now closed
⇒View Archives here⇐
Organizing Committee:
Faculty from UMBC and Stanford University and leaders from FDA and industry.
For more information:
Please contact Dr. Yi Huang, Department of Mathematics and
Statistics, University of Maryland Baltimore County (UMBC),
1000 Hilltop Circle, Baltimore, MD 21250.
E-Mail: yihuang@umbc.edu.
For any Technical difficulties Please contact Zana Coulibaly at czana1@umbc.edu.
Participant Information
Lei Nie from US Food and Drug Agency.
Paper: Innovation of dose finding in Oncology: brief discussion
The traditional MTD based approach, which select the maximum tolerated dose as the recommended dose for registration trials is not an optimal choice for the development of targeted therapy. We briefly explain why the traditional approach does not work and discuss a few new innovations for the development of targeted therapy, including estimation based dose finding strategy, integrated dose finding approach, seamless adaptive design approach.