Event Summary:
A one-day workshop organized by the Center for Interdisciplinary Research and
Consulting at the University of Maryland, Baltimore County (UMBC), and the
Center for Innovative Study Design (CISD) at Stanford University in the field of Clinical Trials and Regulatory Science.
Registration is now closed
⇒View Archives here⇐
Organizing Committee:
Faculty from UMBC and Stanford University and leaders from FDA and industry.
For more information:
Please contact Dr. Yi Huang, Department of Mathematics and
Statistics, University of Maryland Baltimore County (UMBC),
1000 Hilltop Circle, Baltimore, MD 21250.
E-Mail: yihuang@umbc.edu.
For any Technical difficulties Please contact Zana Coulibaly at czana1@umbc.edu.
Participant Information
Kaifeng Lu from Allergan plc.
Paper: Comparison of graphical and gatekeeping procedures for multiplicity control in clinical trials
Multiplicity problems abound in confirmatory controlled clinical trials. Strong control of the familywise error rate (FWER) is often a prerequisite for obtaining regulatory claims in the product label. Graphical and gatekeeping procedures are two popular and powerful multiple testing procedures for addressing multiplicity issues in the analysis of randomized clinical trials. We will compare these two classes of methods in terms of power, flexibility, ease of communication, and availability of software implementation using clinical trial examples.