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Sponsored Programs Review of Grants The UMBC Office of Sponsored Programs (OSP) will review all grant applications involving vertebrate animals. When an application is being submitted, the OSP will review and confirm that all information (i.e., the protocol’s latest approval date and the institution’s assurance number) is correct. If a protocol is pending, the word “PENDING” should be written in the space asking for the protocol’s latest approval date. The NIH currently allows a 60-day grace period for the institutional approval letter to be submitted. If the application is being submitted to another funding source, which requires a special letter indicating protocol status, the Human and Animal Research Protections Office (HARPO) will issue these letters. The IACUC Chair or the Administrator, Human and Animal Research Protections Office are the only individuals authorized by the IO to verify that the activities described in PHS Applications, PHS Form 398, are congruent with those approved by the IACUC-or visa versa. These individuals will work in concert with the Office of Sponsored Programs to review those sections of applications and proposals related to the care and use of animals. HARPO, on behalf of the IACUC Chair, will notify investigators of the IACUC’s decision to approve or withhold approval of those sections of applications or proposals related to the care and use of animals, or of modifications required to secure IACUC approval as set forth in “PHS Policy” at IV.C4. Principal investigators of externally funded projects bear the responsibility of providing written notification to granting agencies requiring such notification of approval. A copy of this notification must be forwarded by the investigator to HARPO. Collaborations When research involving vertebrate animals will take place at collaborating site(s) or other performance site(s) that have their own IACUC, the UMBC Principal Investigator should provide this information in a cover letter that accompanies the application. In these cases, the protocol and IACUC approval from the collaborating site(s) will be acceptable, provided all supporting correspondence is also provided. The UMBC IACUC may ask additional questions of the UMBC investigator. Also, the UMBC investigator must complete the cover sheet and the assurance form for UMBC. Finally, any such approval cannot exceed the duration of the approval obtained from the other institution. Public Health Service (PHS) 398 Grant Applications Requirements for Institutional Review of Section 2F - Vertebrate Animals Section 2F in PHS grants must be completed for all new and competitive renewal applications. Section 2F should contain all of the information which the NIH has specified shall be included in this section: Provide a detailed description of the proposed use of the animals in the work previously outlined in the experimental design and methods section. Identify the species, strain, age, sex, and number of animals to be used in the proposed work Justify the use of animals, the choice of species, and the numbers used. If animals are in short supply, costly, or to be used in large numbers, provide an additional rationale for their selection and their numbers Provide information on the veterinary care of the animals involved. Include the following statement: Animals are maintained in the centralized animal facilities of the University of Maryland Baltimore County (UMBC) Animals are housed, cared for, and used strictly in accordance with the NIH Guide for the Care and Use of Laboratory Animals, 1996. UMBC has a category 2 approved program assurance on file with NIH. Veterinary care is provided by specialty-trained laboratory animal veterinarians at UM. This institution has an Animal Welfare Assurance on file with the NIH Office for Laboratory Animal Welfare (OLAW)), Assurance Number A3784-01.
Describe the procedures for ensuring that discomfort, distress, pain, and injury will be limited to that which is unavoidable in the conduct of scientifically sound research. Describe the use of analgesic, anesthetic, and tranquilizing drugs and/or comfortable restraining devices where appropriate to minimize discomfort, distress, pain, and injury Describe any euthanasia method to be used and the reasons for its selection. State whether this method is consistent with the recommendations of the Panel on Euthanasia of the American Veterinary Medical Association. If not, present a justification for not following the recommendations Although no specific page limitation applies to this section of the application, be succinct. |
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Last updated 04/28/2008 |
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